Naturally phytoalexin produce » resveratrol side effects

Resveratrol Is Known To Help Type 2 Diabetes

resveratrol — Mon, 04 Jan 2010 08:01:00 +0000

Natural health experts believe that type II diabetes is a nutritional disease, when no other cause can be identified. In other words, incorrect nutritional intake over a period of many years leads to the metabolic disorder that is usually accompanied by a tendency towards obesity and high blood sugar levels.

Will a pill someday be able to prevent some of the most debilitating effects of aging, including cancer and diabetes. It is promising to think that accelerated aging, diabetes and cancer could one day be treated with this natural compound. As a drug, resveratrol may one day be used to treat fresh heart attacks and strokes, diabetes, as well as brain trauma.

Resveratrol has captured the attention of the world’s health and scientific communities since experiments from the Harvard laboratory of David Sinclair first appeared in the journal Nature in 2003. Resveratrol is the antioxidant compound in red wine that is currently hyped as the new “fountain of youth”.

Resveratrol is fast becoming one of the health buzz words of the decade. With studies now showing that resveratrol may well have significant effects on such cancers as prostate and breast cancer, the news is good. But is there a link between resveratrol and diabetes as well?

According to recent studies of resveratrol and diabetes, there seems to be growing excitement about a potential breakthrough, so what is this all about? We have known for a long time the powers of this super nutrient in stopping cancer and increasing life expectancy, but according to the latest research, an imminent breakthrough is predicted for type 2 diabetes.

One of the latest resveratrol and diabetes studies has to do with a novel function. One of the things that occur in type II diabetics is that amylin, a protein peptide that is released by pancreatic cells along with insulin, begins to form hard fibrils within the cells. These fibrils eventually kill the cell. Resveratrol inhibits the formation of these fibrils, according to a recent study.

It truly has some remarkable positive health effects for all of us without any resveratrol side effects that are negative. Even better if you want to get the ultimate benefit of it take it in a combined supplement that includes other health promoting ingredients like the one I take which has over 70 ingredients that comprise of products like decaffeinated green tea and turmeric, to name a few.

What is the right Resveratrol Dosage?

resveratrol — Sun, 03 Jan 2010 08:51:49 +0000

Interested in adding resveratrol to your diet? If you’ve been hearing the recent news about resveratrol’s profound effects found in recent studies, including anti-cancer properties, weight loss, and longevity effects, there’s a good chance that you are thinking about trying it yourself. There are many different foods and drinks that provide resveratrol, including red wine, peanuts, and even cocoa. There are also numerous companies that have developed Resveratrol supplement, a great way to get your daily dose. But how much should you take a day? What is the recommended resveratrol dosage to experience these wonderful health benefits?

First, it’s important to know that there have been very few studies carried out on humans in regards to resveratrol effects, supplementation, and dosage guidelines. Nearly all research has been done on insects and mice, and trying to extrapolate a dosage from animal results to human recommendations is a difficult achievement. However, scientists are attempting to address the question of resveratrol dosage for human use from several different approaches. The data resulting from studies done on mice has offered some clues, and scientists are actively searching out more.

In the meantime, some initial recommendations have been developed for resveratrol dosage in humans. At the human equivalent of a 20 mg resveratrol capsule dose a day, mice experienced pronounced anti-aging gene-expression changes, according to studies carried out by one pharmaceutical company. A daily dosage of 20 mg of resveratrol seems like a good starting point when you consider the other end of the spectrum.

One Company that offers low dose resveratrol supplement of 15mg of resveratrol ultra – they recommend taking two 15mg capsules twice a day because resveratrol activation effects, they say, last about 9-10 hours in the body. So, inorder to keep the Sirt 1 gene activated for most of the 24 hr period and get the maximum benefit, taking a few low dose resveratrol supplements a day is potentially more effective and less likely to cause side effects that may exist in larger dosed supplements.

Another manufacturer claims that mega doses of their supplements should be of no concern – ‘mega doses’ being defined as 500 – 1000 mg per dosage. However, in a volunteer study of participants taking mega doses of resveratrol, there were some side effects experienced – all reversible – that included abnormal blood tests, anemia, diarrhea, anxiety, and over-thinning of the blood. This should tell us succinctly that taking a high dosage of resveratrol is not in our best interest. It seems wise to be moderate when deciding on a dosage for a new supplement. For a 150 pound person, this would equal an approximate recommendation of a 334 mg dosage of resveratrol. In that light, it makes sense to consider dosage guidelines in the view of a person’s weight in order to determine how their body will respond. It would make sense that a 300 pound person would have much different results with a mega dosage of resveratrol than a 150 pound person.

But there is one thing has to be considered that resveratrol overdose can cause some dizziness, high blood pressure and mild headaches. Resveratrol supplement is the best if taken in limit.

The Cancer Cure/Resveratrol Link

resveratrol — Sat, 02 Jan 2010 04:14:35 +0000

If you’re interested in the cancer cure/resveratrol link there’s good news. Science is on the way to showing the beneficial effects on cancer. But don’t wait 10 or more years to try it for yourself, take the worlds best nutritional supplements with 32 mg of resveratrol per tablet.

It is not only the Resveratrol and prostate cancer link which is cause all the excitement but many others too such as helping with Alzheimer’s and diabetes. All this is especially great news for men, that we can potentially fight off this increasingly common disease.

Research suggests resveratrol not only reaches its intended target, injuring the nexus of malignant cells, but at the same time protects normal tissue from the harmful effects of radiation. Yes, you have a double therapeutic gain as it makes tumor cells more sensitive to radiation, and makes normal tissue less sensitive!

One study concerning Resveratrol prostate cancer treatment and prevention combined the antioxidant with other phytochemicals found in the skins of muscadine grapes. They called it muscadine grape skin extract or MSKE for short.

Muscadines (Vitis rotundifolia), are a particular grapevine species native to the present-day southeastern United States that have been cultivated extensively since the 16th Century.

Muscadine grape vines are largely immune to fungus, nematodes and bacteria and insects rarely cause any damage. Resveratrol from muscadine grapes is widely believed to cure prostate cancer. Resveratrol has many healing properties and Muscadine grapes, where it is found in abundance, were used in laboratory tests.

The antioxidant properties of the muscadine grapes have now come to the fore. It is perhaps the best fruit made available to humans for protection against a dozen ailments.

In addition, there are a group of nutrients that work in “synergy” with resveratrol to provide the greatest anti-cancer effects. These same anti-cancer affects can help protect the body from heart disease and other life-threatening diseases, in which chronic inflammation plays a role.

You should also look for one that contains saw palmetto, lycopene, nettle root, zinc and red clover, both of which support the prostate’s health. In order to get the most from Resveratrol and prostate cancer prevention provided by it, be sure that the supplement has an enteric coating to protect it from stomach acid. Keep watching for more Resveratrol prostate cancer news and learn about other interesting phytochemicals.

For example, Resveratrol combines well with green tea extract among others, and it is this beneficial interaction or synergy that greatly amplifies its power to fight cancer, and many other diseases. Perhaps in the future, as we become more and more aware, we could help to eradicate this deadly disease by taking preventative steps, rather than looking for a cure.

Since the resveratrol and prostate cancer benefits are often not negligible with drinking red wine, it is recommended that a multi-vitamin supplement that contains this nutrient is the best way to consume it.

The Goodness and the Wonder Effect of Resveratrol

resveratrol — Fri, 01 Jan 2010 04:44:00 +0000

http://resveratrol.trevorz.com/

X’tranol-24TM Working at the Cellular Level to Keep Energy Levels Operating at a Maximum, Anti-Aging

If you thought biology class was the last time you would hear about cells, think again. We are completely composed of cells and without them we would not be alive. How well your cells perform is a direct reflection of how well your body performs.

Cells constantly need to duplicate. Healthy cells duplicate new healthy cells and damaged cells duplicate damaged cells. Each cell requires energy to do its job and to duplicate itself. The organelles in the body that generate energy in each cell are called the mitochondria.

As we age and/or subject our bodies to stress, mitochondria tend to slow down their reproduction and emit less energy, leaving our bodies more disease-prone and causing an overall decline in health. How quickly and severely this happens is based upon our diet, nutrition, rest and exercise (to name a few).

Fortunately, there is resveratrol which works to clean and invigorate the organelles, keeping the mitochondria operating at maximum efficiency. This leads to better health and more energy. It’s a true anti-aging remedy.

X’tranol-24TM contains standardized levels of resveratrol in every serving so you know your body is getting what it needs so you can continue to live your optimal healthy lifestyle. But it goes beyond resveratrol. Triple-patented X’tranol-24 also provides all the nutrients, polyphenols, anthrocyanins, flavonols, and other micro nutrients found in red wine, without the alcohol, plus enteric coated primary antioxidants. And, most of all, it tastes terrific! Try it; you won’t believe the difference it can make in your life.

Remember, your best source of resveratrol is Symmetry’s GenesisTM! Drink up!

Resveratrol as Anti-aging Antioxidant

resveratrol — Thu, 31 Dec 2009 09:41:15 +0000

Resveratrol supplements are the latest antiaging fad. Aging is breakdown, but broken things can be fixed. Aging is characterized by a progressive deterioration of physiological functions and metabolic processes. The healthy reputation of dietary antioxidants just got more support, with one type turning in a spectacular anti-aging performance.

Research studies continue to find more interesting benefits from this red wine compound, including potential anti-cancer and anti-aging activity. As to its antiaging potential, resveratrol activates a cell’s survival defense enzyme, which prolongs the time cells have to repair their broken DNA.

Newspapers, magazines and TV over the last few years have been filled with news of the anti-aging, antioxidant and seemingly miraculous properties of red wine. Wine lovers are probably already aware that red wine contains a powerful antioxidant: resveratrol.

Resveratrol appears to work as a powerful antioxidant helping quench free radical damage in the body, but also has a unique mechanism of action that may prove to have significant life extension properties. Antioxidant resveratrol action is very important for the heart health because it can reduce the blood pressure by opening the arteries hence increasing the blood flow through them.

Antioxidants slow down cell damage and the progression of degenerative diseases such as heart disease, diabetes, cancer, Alzheimer’s and Parkinson’s and improve organ, eye, skin, teeth and gum health.

The primary health component of wine that researchers have uncovered is called resveratrol. Resveratrol is also found in a number of other foods and berries, such a peanuts and blueberries but grapes, particularly winemaking grapes such as Muscadine, are the clear winner.

Resveratrol maintains cell viability and exerts an anti-oxidative action by enhancing the intracellular free-radical scavenger glutathione. Resveratrol is an active polyphenol found in red wine that has anti cancer effects. Resveratrol is known to fight cancer tumor growth. Resveratrol protects heart tissue from cancer chemotherapy drug. Resveratrol is known to be protective against oxidative cardiovascular disorders.

Resveratrol protects the circulation in the heart and other organs in several ways, including protection against ischemic-reperfusion injury, relaxation of blood vessels to improve circulation, protection and maintenance of intact endothelium, reduction of hardening of the arteries, inhibition of low-density lipoprotein oxidation, and suppression of platelet aggregation which improves blood flow and reduces blood clotting.

Resveratrol helps lower cholesterol, and is as much as 10 to 20 times more potent than vitamin E in protecting against LDL oxidation, a process that has been linked to the development of cardiovascular disease. Resveratrol in wine is known to prevent blood clots and widen (dilate) blood vessels, sometimes producing Viagra-like effects. Resveratrol pills should ideally be consumed with meals, since this is when insulin and blood sugar levels rise and when oxidation is high.

Resvinatrol Complete contains the powerful red wine antioxidant, resveratrol, called « The Fountain of Youth » in a formula that includes several other important antioxidants. Resveratrol, just one of the powerful antioxidants in Resvinatrol Complete, is being heralded by scientists and researchers as an anti-aging miracle drug that can help ward off the effects of age-related diseases such as cancer, heart disease, strokes, obesity, diabetes and Alzheimer’s.

Resvinatrol Complete provides today’s health-conscious consumers with an exciting combination of powerful antioxidants found in red wine, chocolate, pomegranates, red raspberries, and soy. Resvinatrol Complete’s combination of antioxidants is unmatched by any other antioxidant product on the market today.

Resveratrol Supplements: or Just Polish Off the Merlot

resveratrol — Wed, 30 Dec 2009 08:36:16 +0000

The popularity of the Mediterranean Diet and it’s apparent impact on longevity has led to research into the substance resveratrol, an ingredient found in red wine and a diet staple in the Mediterranean culture.

After extensive experimentation, doctors have concluded that resveratrol demonstrates the ability to reverse the effects of obesity in mice. In addition, they observed that mice placed on a diet of resveratrol supplements also exhibited higher endurance levels and longer lifespans than mice on a non-supplemented diet.

In a controlled test environment, ordinary mice will normally run approximately one kilometer on a treadmill before collapsing in exhaustion. However, mice that have been given a resveratrol supplement will run twice as far before showing evidence of tiring. In addition, subsequent tests also show that the mice on the resveratrol program demonstrate heightened muscle control and strength and have a significantly reduced resting heart rate when compared to the ordinary mice.

After the success of resveratrol supplement testing on mice and other animals, doctors at the Institute of Genetics and Molecular and Cellular Biology in Illkirch, France have now completed initial human experiments that demonstrate that similar results can be obtained in human test subjects that are placed on a program of high quality resveratrol supplementation.

The key to resveratrol’s effects on the body are in the substance’s ability to work at a cellular level to increase the production of mitochondria. Mitochondria are the organisms in the body that generate energy. The extra mitochondria in the treated mice resulted in the ability to burn more fat and to optimize muscle functions.

Dr. Ronald M. Evans, a scientist at the Salk Institute and an expert on the hormonal control of metabolic functions, stated that the report by the French genetics team had “shown very convincingly that resveratrol improves mitochondrial function” and wards off metabolic disease. Evans characterized described the study as “very important, because it is rare that we identify orally active molecules, especially natural molecules, that have such a broad-based, positive effect on a problem which is as widespread in society as metabolic disease.”

A drug that can prevent degenerative disease, promote weight loss, prolong life, and reshape an individual into a highly trained athlete sounds like the stuff of science fiction. But doctors are convinced that their work into the effects of resveratrol and resveratrol synergy have led to some surprising advancements in the area of anti-aging. They now believe that the body’s ability to utilize sirtuins, enzymes that protect and energize our systems, declines with age. This is the process that is reversed by resveratrol.

The growing evidence supporting the benefits of resveratrol has enthused scientists who do research on the aging process, several of whom are already taking resveratrol supplements. Dr. David Sinclair, a scientist at the anti-aging drug research company Sirtris, has been taking resveratrol supplements in liquid and capsule form for over three years. He claims that half the members of his laboratory do the same and that he is encouraging use of the supplements to family and friends. There are a range of views on appropriate resveratrol dosages, but this involves detailed debate around ingredient purity and potency.

Quality resveratrol supplements are designed to maximize the efficicencies of formula and dosage.

Purchase the Best Certified Resveratrol Supplements – You Can Do it With These 3 Easy Steps!

resveratrol — Mon, 28 Dec 2009 20:44:20 +0000

So, you want to purchase the best certified resveratrol supplement available online? The solution to that question should be yes. If you are not attempting to purchase a resveratrol product then I am not sure why you would be taking a look at this educational article. Anyway, today you are going to learn about 3 steps that will make buying resveratrol supplements a breeze. All thatyou need to do is use the information which I have presented you with for free to your benefit.

Alright then, move on to the subsequent section to start reading about the 1st step that goes into getting your 100% guaranteed satisfaction free trial. This will the best way for you to obtain only the best resveratrol products…

Be practical About What Resveratrol supplements Can Offer You

towards purchasing the best health supplement possible is to start being pragmatic. Sounds ridiculous when it comes to purchasing a health product, right? Incorrect. Being down-to-earth about what resveratrol products can offer to you is essential when it comes to getting the best product possible.

You understand that this supplement will not solve all of your issues instantly. While resveratrol is a great health supplement which offers plenty of health benefits, it is in no way, shape, or form a ‘magic pill’. If this is what you see resveratrol as then you have 2 options. You may either throw in the towel on buying a resveratrol supplement or you could start realizing that it isn’t a wizardry pill.

Make sure that This Health Supplement Is The Right Health Supplement

This next step goes hand in hand with the 1st one. After lowing your expectancies and being more practical about what resveratrol can offer to you, you will have to guage whether resveratrol supplements are the right sort of supplement for you. You need to ask yourself,’What is it that resveratrol can offer in terms of health benefits and is it applicable to me?’.

You see, resveratrol offers many great health benefits such as weight loss benefits, anti-aging benefits, cardiovascular performance increases, diabetes prevention, and much more. But if these types of health benefits are not relevant to you then whatis the point of taking a resveratrol nutrient or buying it in the 1st place?

Use A Resveratrol purchasing Guide

The ultimate step to buying the best resveratrol nutrient possible is to employ a buying guide which covers all of the essentials. A guide will not only allow you to access only the best supplements possible but it will also tell you how exactly to buy resveratrol, inform you of the best prices, and a whole lot additional information relevant to purchasing the health supplement.

Now note that big US TV channels and newspapers have brought excellent reviews about resveratrol effects. They say it will will help you:

- Slown down your aging process

- Extend your life

- Lose weight

- Override an unhealthy lifestyle

- Boost your energy levels

Even after that if you are still trying to figure out what the benefits of resveratrol are, here is what one of the official websites explains about this new revolution:

"Resveratrol has been the subject of some of the most exciting anti-aging research in decades and only recently has become available in purified form.

Resveratrol is a high potency, all-natural supplement that provides high levels of one of the most powerful naturally occurring anti-oxidants. It is commonly found in Red Wine and is well-known as a principal part of the healthy Mediterranean diet. We’ve naturally concentrated the goodness of wine’s most beneficial molecule without having to consume a signle drop of alcohol".

Don’t wait any longer check it by yourself right here.

Does Resveratrol in Red Wine Solve the French Paradox?

resveratrol — Fri, 25 Dec 2009 09:15:53 +0000

Resveratrol is a polyphenol type flavonoid currently exciting great interest as a potential boon to health. Like other flavonoids and polyphenols, it is a very useful anti-oxidant in its own right, but resveratrol has attracted particular attention as a potential solution to the so-called “French Paradox”.

This is the term used to describe the phenomenon, which has long been a puzzle to medical science, by which rates of cardiovascular disease in France have remained low relative to those in the rest of the developed world, despite the widespread national consumption of a diet high in animal fat and cholesterol, and a firmly entrenched tobacco habit. Of course France also enjoys many of the benefits of the so-called Mediterranean diet through its high intake of fresh fruit and vegetables, oily fish and olive oil, but there are good reasons to think that the consumption of red wine may be the real explanation of the apparent paradox.

It is known in any case that the moderate consumption of alcohol has a significant protective effect on the cardiovascular system, reducing disease by as much as 20-30%, but conventional medical opinion is characteristically cautious in acknowledging that the resveratrol in red wine may have any benefits over and above those which would in any case be provided by the alcohol. However, the role of fat-soluble anti-oxidants in protecting the circulatory system from damaging free radical attack is well understood, and it would therefore appear that the resveratrol and other polyphenols contained in red wine can only be beneficial. Laboratory tests, moreover, have shown resveratrol to have significant anti-coagulant and anti-inflammatory effects.

For the purposes of obtaining your intake of resveratrol from wine you need to know that it’s contained principally in the skins of red or black grapes, and is consequently found in significant quantities only in those wines produced by an initial pulp fermentation which allows the developing alcohol to leach both colour and other substances, including resveratrol, from the skins. It follows that the longer this pulp fermentation is allowed to continue the more resveratrol the wine will contain. So the colour of the wine is a handy guide. Generally, the richer and darker the colour of the wine the more resveratrol will be found. Rose types and light reds may contain some, but white wines produced by a juice fermentation alone will provide little if any.

Usually it is the red wines produced in the sunnnier climates close to the Mediterranean, and the New World, which will be richest in resveratrol, and dark red wines of this type may provide as much as 2 mg of resveratrol in a small 5 oz glass. But unfortunately from a health point of view, these also tend to be the strongest in alcohol and the so-called “congeners” which accentuate hangovers.

But fortunately for those who dislike red wine, or are concerned about alcohol intake, other sources of resveratrol are available. The amount in foods varies widely, but the best sources are peanuts and red grapes, both of which may provide anywhere between 0.3 and 1.3 mg of resveratrol per cup. Bilberries and cranberries may also be a useful source.

Supplements of resveratrol are also now readily available, principally in the form of red wine or red grape extracts, which will also contain other anti-oxidant polyphenols. Manufacturers’ recommended doses will typically provide between 10 and 50 mg of resveratrol, which would require a very high, and potentially hazardous, level of wine consumption to achieve regularly.

That said, there is no known toxicity from taking resveratrol, as such, although its blood thinning properties will tend to inhibit the blood’s clotting ability and resveratrol is therefore not recommended for those taking anti-coagulant drugs such as warfarin, or certain types of anti-inflammatory including aspirin. Needless to say, however, toxicity problems of a different kind may occur if alcoholic drinks are used to excess as the principal or only source.

But as noted above, moderate consumption is generally recognised to be beneficial to health, particularly for the cardiovascular system. So the message seems to be: if you want to enjoy a couple of glasses of wine with your dinner then go right ahead. And have that age old pleasure enhanced by the knowledge that the resveratrol it contains is also doing you some good.

Resveratrol Effects – What Does Resveratrol Really Do?

resveratrol — Tue, 22 Dec 2009 00:24:17 +0000

Who else wants to know about real resveratrol effects on the body? If you are reading this right now, and are concerned about your health and well fare, I’m going to guess you probably already have a loose idea about resveratrol research, and how it MAY be able to help you live longer, live healthier and live HAPPIER as well. But if you aren’t entirely sure about the real effects of resveratrol, yet, your interested in learning more…..this article was written with you in mind!

Filed Under: OK… so how is resveratrol supposed to help my health?

Well, the truth is, scientists are NOT yet completely sure. What they do know, for certain, are the effects that resveratrol has in laboratory experiments, most notably on animal subjects. In many trials, this mysterious compound has given “new life” to mice, rats, fish and even fruit flies! Scientists have studied the “caloric restriction” effect that resveratrol seems to have as well, which means that even when fed an ordinary diet, animals supplemented with resveratrol seem to “mimic” the effect of being on a strict diet, which is one of the hallmarks of healthy life and life extension as well.

What about cancer and serious disease? Will resveratrol help to cure me of grave illness?

There is NOT enough conclusive proof to say for sure, but clearly, at this point, you would not want to “count” on this style treatment for anything that is life threatening, or potentially very grave. With that said, there have been amazing insights with resveratrol and cancer, with some widely reported clinical trials showing that supplementation seems to kill breast cancer cells in a test tube, and some equally significant findings in men suffering from prostate cancer as well. (please note: While encouraging, these remain yet to be proven in repeatable trials with real bodies like ours, so don’t get TOO enthusiastic just yet!)

Bonus Tip:

Beware of the Resveratrol Scams! Unfortunately, many of the resveratrol products on the market are scams, being sold by unscrupulous companies with one hand in your pocket, rather than out to help you heal.

My best advice? If you really want to experience the amazing anti aging benefits of this powerful anti-oxidant , make sure you ONLY buy

Genuine Resveratrol Supplements or extract.

Also, you can check out Real

( Resveratrol Trials and Reviews like these that will help you make a smarter, more informed, and ultimately BETTER buying decision as well!)

Burn Fat and Boost Energy With Resveratrol

resveratrol — Sun, 20 Dec 2009 22:48:21 +0000

Resveratrol is constantly in the news and on TV now. So what’s all the hype about this thing called Resveratrol? To answer this question, I give a short explanation of what Resveratrol is, what it does and how it works:

What is Resveratrol?

Resveratrol is a polyphenolic compound found in grapes, red wine, purple grape juice, peanuts, and some berries. Large quantities of anti-oxidents and Resveratrol are found in the skins of grapes; hence the Resveratrol supplement has been labeled “the wine pill”. Plants make Resveratrol to protect themselves against the effects of poor growing conditions, severe weather and attacks by insects and disease.

Resveratrol exists in two different isomers: trans-Resveratrol and cis-Resveratrol. The prefixes refer to the shape of the molecule. When taken orally, Resveratrol appears to be well-absorbed by humans. As a consumer, you are only concerned with “trans-Resveratrol” because it is the biologically active one of the two isomers. It is the one that produces the desired effects that everyone is raving about.

So what exactly will a Resveratrol supplement do for me?

There are many desired effects of taking Resveratrol. Let me just say that Resveratrol naturally activates our “longevity gene” (the “sirtuin SIR genes.) This has many desired effects such as a boost in energy, fat burning efficiency, increased ability to focus mentally, decrease in the sensitivity in the bowels caused by irritable bowel syndrome (IBS), reduction in coronary heart disease, and more.

Resveratrol Effects on Cholesterol:

Resveratrol prevents age-related and obesity-related cardiovascular functional decline. It effectively scavenges (neutralizes) free radicals and other oxidants and inhibits low density lipoprotein (LDL) oxidation. The chemical structure of Resveratrol is very similar to that of the synthetic estrogen agonist, diethylstilbestrol.

In estrogen receptor-positive breast cancer cells, Resveratrol acted as an estrogen agonist mirroring the effects of diethylstilbestrol. Resveratrol also has been found to inhibit the expression of adhesion of inflammatory white blood cells from the blood to the arterial wall by vascular cell adhesion molecules.

Resveratrol has also been found to exert a number of potentially cardioprotective effects including inhibition of platelet aggregation and promotion of vasodilation by enhancing the production of inflammatory enzymes.

Resveratrol Effects on Cancer:

Resveratrol has been found to inhibit the proliferation of a variety of human cancer cell lines, including those from breast, prostate, stomach, colon, pancreatic, and thyroid cancers.

Following DNA damage, the cell cycle can be transiently arrested to allow for DNA repair or activation of pathways leading to cell death. Resveratrol has been found to inhibit the activity of certain cytochrome enzymes which promotes the excretion of potentially toxic or carcinogenic chemicals. Resveratrol helps prevent cancer by decreasing exposure to these activated carcinogens.

Resveratrol is not known to be toxic or cause adverse effects in humans. It is completely natural. We are learning a great deal about how Resveratrol affects the health and survival of humans, with many promising new approaches being discovered every day. The continued study of calorie restriction mimetics like Resveratrol help point the way to creating new medicines that treat the disease of aging.